Art, culture, and aesthetics constitute an integral dimension of Indian Knowledge System(IKS), reflecting a holistic understanding of human creativity, social life, spirituality, and cultural continuity. Unlike purely utilitarian perspectives of art, the Indian tradition regards artistic expression as a means of knowledge transmission, emotional refinement, ethical development, and spiritual realization. Across centuries, India has developed rich traditions of music, dance, drama, architecture, sculpture, painting, literature, crafts, and oral narratives that embody philosophical insights, social values, and collective memory. These artistic traditions have functioned not only as cultural expressions but also as dynamic repositories of indigenous knowledge, contributing to the preservation and dissemination of intellectual, ecological, and ethical wisdom. This chapter explores the foundations of art, culture, and aesthetics within the framework of Indian Knowledge Systems. It examines the philosophical basis of Indian aesthetics, particularly the concepts of Rasa, Saundarya, Satyam-Shivam-Sundaram, and Ananda, which have shaped artistic theory and practice for centuries. The chapter analyzes the significance of the Natyashastra as a foundational text of aesthetic thought and discusses the development of classical dance, music, architecture, sculpture, painting, and literature as interconnected forms of cultural knowledge. Special attention is given to temple culture, symbolic representations, folk traditions, indigenous artistic practices, and the role of women in preserving artistic heritage. The chapter further highlights the educational, social, and spiritual functions of art in Indian civilization and examines how artistic traditions have contributed to identity formation, cultural continuity, and community resilience. It also explores the global influence of Indian artistic traditions and their relevance in contemporary discussions on cultural sustainability, holistic education, emotional well-being, and sustainable development. The study argues that Indian aesthetics transcends conventional notions of beauty by integrating ethical values, emotional experience, and spiritual consciousness into artistic expression. By examining the diverse artistic and cultural traditions of India through the lens of Indian Knowledge Systems, this chapter demonstrates that art serves as a powerful medium for preserving civilizational wisdom and fostering human flourishing. The continued study, preservation, and revitalization of these traditions can contribute significantly to cultural enrichment, interdisciplinary scholarship, and sustainable human development in the twenty-first century.