Interdisciplinary and collaborative research has become essential for addressing complex issues that extend beyond the scope of any single discipline, including climate change, global health, artificial intelligence, and social inequality. Combining diverse theoretical perspectives, research methods, and institutional expertise increases the potential for innovation and enhances the relevance of research outcomes. At the same time, these collaborations raise important ethical concerns that are often difficult to manage within conventional discipline-based frameworks. This chapter examines the principal ethical challenges associated with interdisciplinary and collaborative research. It focuses on issues such as authorship disputes, unequal recognition of contributions, data ownership and sharing, informed consent, methodological disagreements, and accountability in large and diverse research teams. The discussion highlights how differences in disciplinary practices, institutional policies, and cultural values can create ethical tensions and increase the risk of oversight. The chapter also evaluates the limitations of existing ethical guidelines and emphasizes the need for common standards that can be applied across disciplines and international contexts. Practical strategies for promoting ethical research are presented, including early authorship agreements, transparent communication, interdisciplinary ethics training, effective governance structures, and stronger institutional support. The chapter concludes that maintaining research integrity in collaborative settings requires shared responsibility, clear accountability, and ethical frameworks that are flexible enough to address the complexity of contemporary research.